Polynucleotides are powerful, bioactive molecules derived from DNA and RNA that support skin regeneration at a cellular level. They work by stimulating fibroblasts, increasing hydration, and reducing inflammation, making them a perfect complement to micro-needling treatments for enhanced skin rejuvenation.
This treatment works by stimulating cellular repair, encouraging skin regeneration through the activation of fibroblasts. As a result, it boosts the production of collagen and elastin, helping to strengthen the skin’s structure and improve overall firmness and elasticity. At the same time, it delivers deep hydration by attracting and retaining moisture, leaving the skin feeling more supple and refreshed.
In addition to its rejuvenating effects, it helps reduce inflammation, soothing irritation and accelerating the skin’s natural healing process. This leads to a noticeable improvement in skin texture, minimising the appearance of fine lines, wrinkles, scars, and enlarged pores. It also enhances the results of micro-needling by improving product absorption and maximising treatment benefits. Recovery time is shortened, allowing the skin to heal more quickly, with results that can continue to improve and last for up to 6–8 months after treatment.
Find out more about the polynucleotide treatment process and what you can expect at Rediscovered Skin Clinic.
We assess your skin quality, hydration levels, and areas of concern to decide if skin boosters are the right fit. This is about improving the condition of your skin, not adding volume.
Your skin is cleansed and numbed for comfort, and the treatment areas are carefully mapped out. We’ll talk you through exactly what to expect before we start.
Tiny injections deliver hydrating and regenerative ingredients directly into the skin, improving elasticity, texture, and overall glow. Think better skin, not bigger features.
You may have small bumps or slight redness for 24–48 hours. Skin gradually becomes more hydrated, smoother, and healthier over the following weeks.
Polynucleotides work exceptionally well as part of a combined treatment approach to support skin regeneration and overall quality. While polynucleotides help repair and strengthen the skin at a cellular level, micro-needling and RF micro-needling create micro-channels and stimulate collagen production, enhancing their absorption and effectiveness. Chemical peels improve skin tone and clarity through gentle exfoliation, while skin boosters provide deep hydration and nourishment. Together, these treatments promote healthier, smoother, and more resilient skin.
skincare devices
Micro-needling
Stimulates collagen while polynucleotides repair and regenerate.
Result: stronger, smoother, more youthful skin.
skincare devices
RF Micro-needling
Stimulates collagen while polynucleotides repair and regenerate.
Result: stronger, smoother, more youthful skin.
skin treatments
Chemical Peels
Resurface the skin while polynucleotides support repair.
Result: brighter skin with improved healing and resilience.
skin boosters
Sunekos
Targets hydration and collagen alongside deeper regeneration.
Result: improved elasticity, texture, and skin strength.
skin boosters
Karisma Collagen Biostimulator
Supports regeneration alongside collagen stimulation.
Result: healthier, firmer, more resilient skin.
Save Face is a Professional Standards Authority accredited register and is recognised by the Government, The Department of Health and NHS England.
You will generally start to see improvement in hydration levels in your skin around 1-2 weeks after your first treatment. The best results come in the weeks following as your collagen network is rebuilt.
We can apply a numbing cream to the treatment area for 20 minutes before treatment so the process is not painful although there may be minor discomfort as the product can sting a little.
The results of improved skin hydration and reduced skin pigmentation last 6 to 9 months. This may vary and does depend on factors such as the structure and condition of your skin, lifestyle factors and age.
The procedure has no downtime (although as with any injectable treatment there may be bruising and swelling) and the patient can immediately continue as normal. On occasions there may be significant swelling in the under eye area.
As with all our treatments you will have a full consultation and medical history taken. Treatment with skin boosters is not recommended in the following instances;
If you have a skin infection in or near the treatment area or are unwell in any way (even a cold).
If you have previously experienced allergic reactions to any of the ingredients or local anaesthetic
If you are taking any medicines which affect bleeding, such as aspirin or warfarin, or have a bleeding disorder.
If you are taking steroids or have autoimmune disease.
If you are pregnant or breastfeeding
If you are currently or have recently completed a course of Roaccutane (Isotretinoin acne treatment) in the last 18 months.
If you have suffered from keloid scars, scleroderma or epilepsy
Your skin may have pin prick marks & tiny blebs/bumps at the injection site. There may be some redness, swelling, tenderness, and bruising which should settle within the next few days. Makeup should not be worn for 12 hours.
Please reach out to the team at Rediscovered Skin Clinic
who will be more than happy to help.
Can be performed together.
Micro-needling stimulates collagen, while polynucleotides repair.
Enhances results and recovery.
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Can be combined.
RF targets deeper tissue, while polynucleotides repair.
Results in stronger, healthier skin.
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These are typically alternated.
Peels resurface skin, while polynucleotides support repair.
Improves brightness and skin strength.
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Used within a treatment plan.
Polynucleotides repair, while others boost hydration/collagen.
Improves skin from multiple levels.
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